Phase III readout expected Q3 2027

Vaccines engineered to reach everyone, on time.

VaxGen Pharma designs, manufactures and ships vaccines for the pathogens that keep coming back — respiratory, enteric and pandemic. Ten programmes in development, four GMP sites, and a cold chain that holds its temperature across 174 countries.

Dublin, Ireland · Founded 2011 · NASDAQ: VXGN

Rows of sealed vaccine vials with blue caps on a production bench
Batch VG-B24-7719 Released in 21 days
A clinician administering an intramuscular vaccine to a patient
Programmes 10 active
Cold-chain integrity 99.98%
0 Doses of annual fill-finish capacity across four GMP sites
0 Countries reached by our qualified cold-chain network
0 Doses delivered since first licensure in 2015
0 Of revenue reinvested into research and development
EU GMP Annex 1US FDA · BLAWHO PrequalificationEMA Marketing AuthorisationISO 9001:2015ISO 13485PIC/S SchemeMHRA LicensedHSA SingaporeANVISA Brazil
The VaxGen platform

One antigen engine. Three engineering rules.

Every programme we take into the clinic has to survive the same three questions: does it make the right immune response, does it stay potent in the vial, and can we make it at scale if it works. We design for all three from day one.

Three-dimensional molecular model of an engineered antigen
Antigen designStructure-guided stabilisation of prefusion and nanoparticle immunogens, screened in silico before a single bench run.
A multichannel pipette loading samples into a 96-well assay plate
Rule 01 · Immunogenicity

Design the response, not just the antigen

Adjuvant matching and immunogen geometry are chosen together, then validated in human-relevant challenge models before Phase I. Every candidate carries a defined correlate of protection at entry.

Rule 02 · Thermostability

Potency that survives the last mile

Our liquid-stable formulations hold 36 months at 2–8 °C without a freezer, which is what makes routine immunisation in low-resource districts actually deliverable.

Rule 03 · Manufacturability

A process that already scales

Every candidate is transferred onto our single-use platform at 2,000 L before Phase II, so a successful trial becomes a licensed product on our own lines — not someone else's queue.

Vaccine pipeline

Ten programmes, four of them in the clinic.

Prophylactic, therapeutic and partner-led candidates across six pathogens. Filter by category, or read the whole chart below.

VG-101Prophylactic

PreFusion RSV

Respiratory syncytial virus · adults 60+

Stabilised prefusion F protein with AS-V3 adjuvant

Phase IIIBLA filing Q3 2027
VG-733Prophylactic

PanFlu H5

Pandemic influenza · H5Nx clades

Recombinant HA nanoparticle, stockpile formulation

Phase III · stockpileWHO PQ 2027
VG-204Prophylactic

TetraFlu mRNA

Seasonal influenza A/B · quadrivalent

mRNA-LNP, strain-updated in 92 days

Phase IIPhase III start 2028
VG-311Prophylactic

DengueGuard

Dengue serotypes 1–4 · endemic regions

Live-attenuated chimeric backbone

Phase IIField data 2028
VG-407Prophylactic

StreptoMum

Group B streptococcus · maternal

Capsular polysaccharide glycoconjugate

Phase IPhase II 2029
VG-620Therapeutic

TBMuc-1

Pulmonary tuberculosis · post-exposure

Mucosal adenoviral vector, inhaled delivery

Phase IDose escalation 2029
VG-512Prophylactic

ShigaShield

Shigella flexneri and sonnei · paediatric

Synthetic bioconjugate, low-cost scale-out

PreclinicalIND filing Q2 2028
VG-905Partner-led

OncoPrime

Personalised neoantigen · solid tumours

mRNA-LNP with Auriga Biologics, our LNP in their trial

Phase I · partnerCombination cohort 2029
VG-912Partner-led

Rabiva

Rabies · post-exposure prophylaxis

Monoclonal antibody cocktail, co-formulated

Preclinical · partnerIND filing 2029
VG-840Prophylactic

CytoVax CMV

Cytomegalovirus · congenital transmission

gB nanoparticle, discovery-stage antigen work

DiscoveryLead selection 2029

Pipeline shown as at 30 September 2026. Programme codes, stage positions and milestone dates are demonstration content for this template.

Download the pipeline chart
Manufacturing capability

We own the lines our vaccines are made on.

Four GMP sites, drug substance through fill-finish, and release testing in-house. That is what lets us promise a pandemic response in 100 days rather than hope for one.

0Doses of annual fill-finish capacity
0Total bioreactor working volume
0Median batch release cycle
0Strain-to-vial pandemic response
A pharmaceutical production hall with stainless steel filling machinery and a controlled clean floor

Dublin aseptic fill-finish hall

Two isolator filling lines running 24 hours a day, four days a week, under continuous environmental monitoring and Annex 1 grade A conditions.

Vials moving through a filling line at the Dublin facility EU GMP

Dublin

Ireland · HQ site

Fill-finish, LNP encapsulation and global quality release for every commercial batch.

140Mdoses / yr
A contamination-controlled laboratory suite at the Singapore site PIC/S

Singapore

Singapore · APAC hub

mRNA drug substance at 2,000 L single-use scale, plus regional release for Asia-Pacific.

60Mdoses / yr
Glassware and analytical instruments on a bench at the Indianapolis site US FDA

Indianapolis

United States · R&D + supply

Recombinant antigen expression and the primary analytical development laboratory.

40Mdoses / yr
Gloved hands loading a tray of vials on the São Paulo filling line ANVISA

São Paulo

Brazil · LATAM hub

Regional fill-finish and release, cutting last-mile delivery times across Latin America.

30Mdoses / yr
01

Single-use up to 2,000 L

Disposable bioreactor trains cut changeover to under 72 hours between programmes.

02

2 × 20,000 L stainless

Stainless-scale capacity waiting for the first commercial launch volumes.

03

LNP encapsulation ≥ 92%

In-line particle sizing on every lot, with the release spec drafted into the BLA.

04

Annex 1 aseptic filling

Isolator lines, grade A unidirectional airflow and continuous viable monitoring.

05

Real-time release testing

At-line analytics remove the traditional end-of-batch wait from the critical path.

06

Vaccine-grade cold rooms

Validated −70 °C, −20 °C and 2–8 °C storage with automated excursion response.

Global distribution

A cold chain measured in integrity, not kilometres.

Six regional hubs, forty-two local depots and a qualified lane for every destination we ship to. Every shipment carries an independent temperature logger, and every excursion is a deviation we investigate.

6 hubs CONTROL TOWER IND DUB SIN SAO OSL DXB
  • IND Indianapolis
  • DUB Dublin
  • OSL Oslo
  • SIN Singapore
  • SAO São Paulo
  • DXB Dubai
0Countries with a qualified shipping lane
0Regional hubs and local depots in the network
0On-time delivery against committed window
0Temperature excursion rate across all lanes
Refrigerated cargo containers staged on an airport apron −70 °C

Ultra-low lane

mRNA-LNP products move in dry-vapour shippers with 10 days of hold-over, monitored to the minute.

  • Dry vapour
  • 10-day hold
  • Live telemetry
Containers stacked at a deep-water port terminal −20 °C

Frozen lane

Viral-vector and nanoparticle products, shipped with validated phase-change panels on ocean and air freight.

  • Phase change
  • Sea + air
  • Reusable
A regional distribution warehouse with stacked pallets of medical supplies 2–8 °C

Routine lane

Our thermostable formulations, stable for 36 months in a standard vaccine fridge — no freezer required.

  • 36 months
  • No freezer
  • National EPI ready
Research partnerships

Nobody develops a vaccine alone.

Our candidates are built with academic immunology groups, tropical-medicine institutes and public-health agencies who hold the challenge models, the field sites and the epidemiology we cannot replicate in-house.

Helix Institute of Immunology

Zurich, Switzerland

Structure-guided antigen design and human-relevant immune profiling for our RSV and CMV candidates.

Since 2019Antigen discovery

Meridian School of Tropical Medicine

Singapore

Controlled human infection models and endemic-site epidemiology for DengueGuard and ShigaShield.

Since 2021Challenge models

Nordic Centre for Pandemic Preparedness

Oslo, Norway

Pandemic stockpile design, strain-watch surveillance and the H5Nx response framework.

Since 2020Pandemic readiness

Pan-American Vaccine Consortium

São Paulo, Brazil

Phase III field networks across seven countries, plus regulatory navigation for LATAM registration.

Since 2022Phase III sites

Auriga Biologics

Cambridge, Massachusetts

Co-development of a personalised neoantigen candidate, pairing their target discovery with our LNP.

Since 2023Co-development

Coalition for Public Health

Geneva, Switzerland

Advance purchase commitments for low-income markets, including tiered pricing and dose donation.

Since 2018Access & pricing
Two researchers reviewing assay data together at a laboratory workstation

How a co-development partnership runs

One funding structure, one integrated team, one joint steering committee. Four stages from first conversation to first participant dosed — typically inside 14 months.

Stage 01

Scope

Six weeks of joint technical diligence on the target, the model and the commercial case.

Stage 02

Feasibility

Bench work on both sides to prove the antigen and the assay translate between labs.

Stage 03

Co-funded development

Shared cost, shared risk and pre-agreed milestone payments up to Phase II readout.

Stage 04

Joint steering

A single committee governs protocol, safety review and publication rights.

Investor relations

A late-stage pipeline with its own manufacturing behind it.

VaxGen lists on NASDAQ and reports quarterly. Two Phase III assets are within eighteen months of filing, four sites are already licensed, and 34% of revenue goes back into the bench.

NASDAQ: VXGN $84.20 ▲ 1.84% Market cap $12.4B

Prices, financials and events shown are illustrative demonstration content for this template and are not an offer of securities or investment advice.

0FY25 revenue, up 28% year on year
0R&D investment in the financial year
0Gross margin on licensed products
0Cash runway funded into this year
  • 12 Nov 26Q3 FY26 results and pipeline updateWebcast
  • 12 Jan 27Healthcare conference — fireside and 1:1sIn person
  • 24 Mar 27VaxGen R&D Day — RSV and H5Nx dataDublin
  • 18 Jun 27Annual general meetingDublin